Fertility Trials

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A double-blind placebo controlled trial of a combination of methotrexate and gefitnib versus methotrexate alone as a treatment for ectopic pregnancy.

Why?

To assess the effectiveness of a combination of methotrexate and gefitinib against methotrexate alone in terms of the need for surgical intervention for ectopic pregnancy.

Who?  

Women aged 18-50 who have been diagnosed with a stable tubal ectopic pregnancy (mass  ≤3.5cm & hCG of 1000–5000 IU/L) and a clinical decision has been made for methotrexate treatment.

Where?

Multi-centre across the UK

Recruitment target

328 women will be recruited across 56 UK sites.

https://www.ed.ac.uk/centre-reproductive-health/gem3-trial/welcome

 

Nicola.Watson@nhslothian.scot.nhs.uk

Priscilla.Fernandez@nhslothian.scot.nhs.uk