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Fertility Trials
A double-blind placebo controlled trial of a combination of methotrexate and gefitnib versus methotrexate alone as a treatment for ectopic pregnancy.
Why?
To assess the effectiveness of a combination of methotrexate and gefitinib against methotrexate alone in terms of the need for surgical intervention for ectopic pregnancy.
Who?
Women aged 18-50 who have been diagnosed with a stable tubal ectopic pregnancy (mass ≤3.5cm & hCG of 1000–5000 IU/L) and a clinical decision has been made for methotrexate treatment.
Where?
Multi-centre across the UK
Recruitment target
328 women will be recruited across 56 UK sites.
https://www.ed.ac.uk/centre-reproductive-health/gem3-trial/welcome
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